DNB CET JUNE 2008

DNB CET 2008 JUNE


Anatomy
1. Deltoid ligament doesn't join medial cuneiform ligament.
2. Scalenus anterior -wrong statement – Subclavian arteries anteriorly.
3. Lainae in substantia geletinosa 2+3.
4. Muscle in deep perineal pouch sphincter urethrae.
5. Persistent primitive streak – sacrococeyge teratoma.
6. Carpal tunnel syndrome – Medial nerve.
7. Pudendal nerve s2-s4 .
8. Pelvic diaphragm consist of levator ani.
9. Abduction of toes is by – Dorsal interossi.
10. Base of 5th metatarsal fracture pull of peroneous brevius.
11. External rotation in semiflexed knee all except – Fibular collteral ligament.
12. Does not pass under extensor, retinaculum – anterior interoseus artery.
13. Section of fibular nerve -Foot drop.
14. Porto Systemic shunt is present at A/E – Lower anal conal.
15. Structure not passing through – inferior cerebellar peduncle- Pontocerebellar.
16. Opthalmic artery is branch of Intra Cranial internal carotid artery.
17. Nucleus ambigus true is - 9th and 10th nerve arise from it.
18. Not a part on Internal capsule – optic radiation.
19. Uterine epithelium develops from fusion of paramesonephric ducts.
20. Boundries of pudendal canal – between obturator membrane and fascia lunata.
21. Diploic bone – frontal.
22. Pain along medical aspect of arm in ca. Breast is through – intercostobrachial nerve.
23. Endinger westphal nucleus belongs to – General Visceral efferent.
24. True about capillaries A/E -Maximum velocity.
25. Functinal of representative hemisphere – steregnosis ( Lesion of representational hemesphere- Astereognosis , Agnosia , unilateral inattension or neglect. Lession iin categorical hemisphere will produce – language disorder.
26. Substantia gelatinosa – laminae ii and iii.


Physiology
1. Circadia rhythm controlled by suprachiasmatic nucleus.
2. Preganglionic sympathetic and parasympathetic nerve secrete – Acetylcholine.
3. Parasympathetic stimulation - inscreases airway resistance.
4. Most important buffer in blood Hb.
5. Inverse stretch reflex – lengthening of muscle
6. Myoglobin is present in slow fibers.
7. Hyperparathyroidism associated with Increase in Alkaline phosphatase.
8. Neurosecretory peptide is somatostatin.
9. Oxtocin – Nerophysin.
10. Intracellular Cation most osmotically active – Na.
11. Splachnic circulation -> 25-30%
12. PH Sensing receptors present in AE -Jugular bulb.
13. PH of blood is -> 7.35 to 7.45
14. Photoreceptor on stimulated release plutamate.
15. Inhibior = Inhibits FSH secretion.
16. True about capillaries – large cumulative surface area ( i.e maximum sectional cross area). Other options -small individual diameter thin wall inscrease velocity.
17. Estrogen seareted by granulosa cells.
18. Intracellular cation most osmotically active – K.
19. Interstitial fluid has most abundant cation is – Na+
20. Arterial Po2 descreases in -None.
Other options – Co poisoning
Ahaemia
Cyanide poisoning
(PAO2 is decreasing in Hypoxic hypoxia)
21. Normal urinary protein excretion - < 150mg /dl
other options – 150-200/200-2500/250-300 mg/dl
The amount of protein in urine is normally less than 100mg/dL.



Biochemistry
1. Allosteric type – bind site other than that of substrate.
2. Telomerase – RNA dependent DNA pohymerase.
3. Degeneracy of genetic code – for 1 a.a there may be more than one codon.
4. Hormone responsive element – DNA sequence where hormone binding protein complex binds.
5. Nota omega -3 fatty acid – linolic acid.
6. B12 is absorbed in Ileum.
7. Iron present in all from except cerulopasmin.
8. Vit D1 , 25 oh , No role of intenstine.
9. Folding and unfolding of DNA – Topoisomerases.
10. HGPRT ( hypoxanthive Guamine phocphoribosyl transferase ) causes salvoge of Hypozanthine of Guanine


Pharmacology
1. Fatty food increases absorption of griseofulvin.
2. Partial agonist – can blind all receptors but produces submaximal activity.
3. Which is most resistant aminoglycoside to enzyme – amikacin
4. Requirment of iron in anamia calculated by wt(kg)/ Hb deficit x 4
5. True about folic acid – required for thymidine synthesis.
6. Pralidoxime c/i in carbaryl poisoning.
7. What will not be found in urine of person consuming multivitamin tables – Cholecalciferol.
8. True bout val proate is cause hepatic Necrosis.
9. Anti- IgE used in asthama in omalizumab.
10. Local anaesthetic used in v local block (Beir's block )- Lidocaine (withoug drenaline)
11. True about cefuroxime – excreted rapidally by kidneys.
12. Granisetron – 5HT3 antagonist.
13. Anti parkinsonian drug with antiapoptotic activity – Selegetive.
14. Shortest acting ACN Esterase – edrophoniun
15. Drug of choice for systemic aspeagillosis – Amphoterian – B (Now voriconazote is drug of st choice)
16. Drug than increases blood level of carbomazapine – Ketoconazole.
* Carbomazole is a substrate as well as induces of CYP3A4
* Ketoconazole inhibit ctochrome p450 especially cYP3A4 and raises the blood levels of carbomazepine
17. Amphotercin B toxicity is monitored b rottasium measurement.
C dose limiting toxicity of amphoteric B is nephrotasicity – manifested by hypokalemia)
18. BZD in hyphotic doses consistenly produce -decreases nocturnal gastric acid secrection other decreases BP / resp-n depresion
19. Highest photosensitivity is seen in pefloxacin.
Option -ciprofloxacin
Ofloxacin
Narflxacin
20. Quinidine is associated a/E – Bradycardia
Other options – SLE
Tachycardia on treading AF Torsades de pointes.




Pathology
1. Delayed type of hypersensitivity is associated with memory CD4 Cells
2. Programmed cell death is called – Apoptosis.
3. Apoptosis true is – cell self initiated.
4. Barr body first detected in buccal mucosa.
5. Falciparum binds to which receptor molecule in brain vascular endothelium – ICAM-1
6. Following is not a tumour marker CEA/ AKP/HCG / thus last option is answer.
7. Alcoholism seen in – Raised ALT i.e SGPT.
8. Thrombosthenin is coontractile protein of platelets.
9. Cryoprecipitate contains – factor VIII and fibriogen ( remember also VWF )
10. Brain changes in crutzfeld jacob disease -spongiform encaphalophaty.
11. Stable Cell – liver cells other stable cells – endothelial , endocringe gland, firboblast ,kidney smoothe muscle cells. These cells are normally non-multiplying but rapidaly multiply in response to stimuli.
12. Cells like Reed steinberg are seen in – Infectious monuclreosis.
13. HMB45 is tumour marker of melanoma Angiomolipoma


Microbiology
1. True about Hepatitis A Virus is A/E – Carrier rate 2%
2. Yellow fever virus is – Flavi virus.
3. Acute HIV infection is diagnosed – P24 antigen capture assay
4. SARS is corona virus.
5. Not a RNA virus – Hepatitis B.
6. Mad cow disease – Protein prion.
7. Infant botulinism true A/E preformed toxin.
8. Superantigen A/E staphylococeus Endotoxin.
9. Toxic shock syndrome (TSS) caused by staphyloco cells aureus.
10. Lysogenic conversion – Diptheria
11. Mc streptococeus in neonatal meningitis lancefield group B
12. Crytcoceus meningitis diagnostic test Indian ink preparation (CSK)
13. Yeast form in A/E Aspergillus.
14. Dignostic test in 1st week of Typhoid blood culture.
15. Typhoid incubation period – 3 to 21 days.
16. Perforation on in typhoids commonly 3rd week
17. Peroff method for sputum microscopy – concentration method that dont kill bateria, Incubation that in 4% Naoh at 37 degree c, Cetrifugation at 30000 rpm for 20 min -Neutralization with N/10 HCL useful for culture and animal inoculation
18. Vibrio Cholerae is characteristic for growth in alkaline medium
19. True about Pseudomonac aeuruginon A/E relatively sensitive to many antimicrobials.
20. Congenital toxoplasmosis occurs if infection acquired in later half of pregnancy in non immune mother.
21. Earliest diagnostic test for .Pylori infection – c/4 breath test.
22. True about polio- man in only reservoir.
23. Cells like reed steinberg are seen in infeactious mononucleasis
24. Antigen belonging to animal and bacteria – Hecterophile antigen
Pathogenic cryptococel grow at 37 Degree C , Hydrolyse urease ( Urease positive ) Lack of fermentative abilit formation of brown pigment on niger seed agar. Ability to assimilate inositol ability to produce phenole oxidase ) polysacoliaride capsule.



FMT
1. Acrodynia – Mercury (Hg) Poisoning )
2. Drug and cosmetic act – import manufacture, distribution , of all drug, controls quality, purity and strenght.
3. Juvenile court - 1st class magistate must be female.
4. Instead of penicillamine can be used in cu poisoning – EDTA
5. chilotic line – seen on hip bone for sex determination.
6. Cholenesterase seen in elapide mainly ie cobra krates, viperade
7. contributory negligence – Avoidable circumstance rute. (ie damaged party cannot recover any damage if he is evern 1% at fault ie injured person mave have contribute to their own injury.
8. Boiled lobster appearance of skin – Boric acid poisoning.
9. Common toxin through vegetable- Oxalic acid.
10. Christmas tree stain is used for identification of semen in a forensic sample.

PSM
1. Neonatal tetonus eliminated when incidence is less than 0.1/1000.
2. Contribution of employer in ESIS 4.75%
3. Clorination of water criteria – clear water.
4. Rat flea – endemic typhus
5. Not transmitted by mosquito – kala azar.
6. Natural mosquito control agent – Pyrethrum
7. Reading of abraded skin by dog – class -z so vaccine only
8. Sllivan's index – Expectation of life free of disability.
9. Entry of pathogen and maximum infectivity – generation time.
10. Definitive diagnosis of leprosy -skin sm ear.
11. Antigen shift is in – Influenza.
12. True of carrier in typhoid – Urinary carrier with anomolly.
13. Shorted incubation period in food poisisning – staphylococcus aureus.
14. Chandless inde - anklostomy anodenale
15. Drakunculosis transmitted by drinking contraminated water.
16. Mltibacillary lerpsy is followed upto – 5 yrs.
17. The concept of female health quide was given by – Kartar Singh.
18. Socrate's method of health education -by Dialectic.
19. Best guide for iron deficiency – serum ferritin
20. Different communities best compared by – age specific death rate.
21. Comfortable tempurature range -77-80 Degree F.
22. Mother to be labelled high risk – Height less than 140 CM
23. Efficiency of malaria elimination programmed is evaluated using ABER.
24. Prophylaxis to maniac person not on medication comming to bihar – Mefloquine
25. Persentage of para para in DTT – 70-80%
26. Carpulence index used in obesity = weight / (Height)2
27. Correct statement – Ans Population density 324/sqkm
a) Population density 324/sqkm, b) TFR-6, c) Growth ration 2:2
28. Triage is used for victim disaster.
29. Epidemiological investigation of choice for kala-azar --> ELISA
DNB CET 2008 JUNE

Surgery
1. Hybatid cyst scolicidal agent not used – Povidine.
2. Barrd's esophagus is – Metaplasia.
3. Not used in Breast ca – Bleomycin
4. Acute papillary necrosis – Diabetes Mellitus.
5. Risk of thromboembolism is higest with femoral vein thrombus.
6. Hyoid bone is related to thyroglossal cyst.
7. Young woman who received mantly radiation in childhood is likely to develop – breast ca.
8. FNAC in testies is indicated in Azzospemia to identify cause / Necrospemrmia / Differentiate between torsion and inflammation / all of above ANS- Necrosppermia.
9. Vaginal Hydrocede is open upto upper pole of testies.
10. Mesothelioma – deacreasing incidence reflects ban on use of abestos.
11. Clot of size of fist accounts for bloods loss of 500ml.
12. Family history is not associated with lung cancer.
13. Renal imaging in pt with allergy USG.
14. MC site of actinomycetes – Jaw.
15. Middle aged man with renal failure with B/L abdominal mass – ADPKD.
16. Lung injury with good prognosis – ope pneumothorox.
17. All caused of painless haematuria except – Acute cstitis.
18. Spindle cell tumour is – Retroperitoneal firbrosis iin infants.
19. Curling ulcer is associated = Burns.
20. Raynaud's phenomenon sequence – Pallor , cyanosis Rubor.
21. Ca not spreading by symphatics – Basal Cell Carcinoma.
22. Increase in risk of colorectal cancer low fiber diet.
23. Most radiosensitive = bone marrow.
24. Breast cancer realted with early menarche.
25. Highest prognostic value in breast cancer – H/O ca in conlralateral breast.
26. Complication of epidural anaesthesia A/E – cord compression / low volume headache / backache / meningitis, Ans-low volume headache.
27. Von meyer complexes seen in Bileduct hamartoma.
28. FNAC intesties is indicated in – Azoospermia to identify couse other options-
1. Necrospermia
2. Differentiate between torsion and inflamation.
3. All of the above.
29. Granuloma with abscess formation crohns disease.
30. Rectus cutting incision – Maryland.
31. Mc solution used for wound debridement – Betamine (Other options -eusol,NS,cetrimide.
32. RCC not true is – more common in females.
33. RCC not true is - Radiosensitive.
34. Narrowest part of male urethea – External meatus.
35. Spindle cell tumour is retroperitoneal fibrosis in infant.
36. Not used for hemostasis in surgery micronised collagen other options – Gel foam / Micronised cellulose.



Orthopaedics
1. Stress not equal (/=) of 2nd metatarsal.
2. Not equal (/=) Neck of femur -External rotation and adduction.
3. Tuberculous spine me site T12/L1
4. Tuberculous arthritls 1st sign – reduced joint space.
5. PID investigation of choice – MRI.
6. Clutton joint Mc cause – Diabetes mellitus.
7. Neuropathis joint not spen in – OM/amyloidosis/leprosy/ sarcoldosis, Ams-Sacroidosis.
[Left side] other options -infections,vascular disease overall injury tumor ,is the commest cause of ampulatio . In elderly 50-75 yrs , PVD perip heral vascular disease in main cause
in younger adults (25- 30 yrs) secondly to injury.
8. Standing on toes not possible in paralysis of gastrocnemius.
9. Card test – Ulnal nerve.
10. Onion Peel appearance – Ewing's Sarcoma.
11. Rheumatoid affect axial skeleton – Cervical vertibrae
12. AVN commonly in Intra capsular /= neck of femur.
13. Rx of choice for postmenopausal osteoporosis – Raloxifine.
14. Nerve regeneration – 1 mm/day.
15. Mc indiacation of omputation – Injury.

Medicine
1. Displacement of apex to left and downward – LVH (Left ventricular hypertrophy)
2. Sinus bradycardia – less than 60.
3. Bloods culture is diagnostic in – infective endocarditis.
4. MCC of infective endocarditis – streptococeus viridans.
5. Atherosclerosis associated infection chlymadia pneumonae.
6. Osler's node – SABE ( Subacute Bacterial Endocarditis )
7. CPAP also A/E – increased cardiac output.
8. Systolic murmur associated with – Ejection click.
9. Physiological murmur associated with A/E – Diastolic murmur.
10. Conn's syndrome – Hyperaldosteronism with Hypokolemia.
11. Pure red cell aplasia is associated with thymoma.
12. Exogenous insulin is differentiated from endogenous by presence of with peptide.
13. Metabolic sydrome is associated with A/E increase in HDL.
14. Chynes stokes breathing – Metabolic alkalosis.
15. Granulomatous condition with hypercalcemia – scircoidosis.
16. Viral meningitis not associated with normal sugar / Normal chloride / lymphocytes / decrease proteins ANS – Nomal chloride.
17. CRF anaemia due to erythropoletin deficiency.
18. Autosomal dominant A/E Beta thallasemia.
19. Mc cause of secondary HTM – Renovascular disease.
20. Hypokalemia produces ECG changes – A/E tall 'T' waves.
21. Agina duration – 15 mins/ 5-10 mins / 15 mins / 30 mins ANS- 30 mins.
22. Unstable angina – cresendo with with normal ECG.
23. Sino atrial disease – Atrial ectopic/ Ventricular ectopic / sinus arrest / sinus arrythmia Ans-Sinus arrythmia.
24. Adenoma sebacenmin Tuberous sclerosis is angiofibroma.
25. Drug induced lupus – anti – histone antibodies.
26. Portwine urine seen in – porphyria / nephritis / melanoma All of the above Ans:- All of the above.
27. Hepatic carcinogen is – Aflatoxin.
28. Liver arrhosis is due to – galactosemia.
29. Pneumocystis carihii pneumonia – inter-alveolar septum.
30. Loud P2 is with pulmonary HTN.
31. Furuncle is caused by – staphylococaus ahreus.
32. Disease causing orchictis – Mumps.
33. Following is not a tumour marker – Melatonin.
34. Ion used in insulin storage – Zn.
35. Mc cause of secondary Hypertension Renal parenchymal disease.
36. Most common organisn of infective endocorditis – Viridans streptococci.
37. Prophylaxis in heart disease for tooth extraction – 1 hr before and two day after.
38. Parentral fat nutrition c/i – Hyperlipidipidemia diabetes malitus / thrombotic states – All of above.
39. Hydropic degenaration of Basal cell seen in – Lichen scterosis atrophicus.
40. Refractory HTN commonest cause pt non compliance.
41. Prophylanis of pneumocystic jiroveei – Symptomatic HIV other options – AIDS / Asymptomatic HIV acut HIV Indication of prophgloris CO4 + T Cell count < 200 / ul or oropharyngcal condidiosis , prior bout of pcp.



Paediatrics
1. Nada's criteria for heart disease.
2. TOF radiological feature A/E Rt sided arch of aorta.
3. Single umbilical artery is associated with congenital anomalies – 10-20%
4. Brown fat is present in A/E check.
5. Fore milk contain A/E – Fat
6. Mc valve associated with rheumatic affection – Mitral valve.
7. Ration of check compression to breath 3:1
8. Thalassemia faces not present. - Antimongoloid slant.
9. 1 yr baby withdiarrhaea, flushing, bone pain, fullness in flanks – Neuroblastoma.
10. Fetal Agemoglobin -(Alpha 2) / Y
11. Hypsrrythmia seen in west syndrome ( Infantile spasm )
12. Citrate added to ORS – To provide base.
13. ASP seen is – Rt axis deviatio n RVH.
14. True about Polia A/E more common in females than males.
15. Juvenile rhenmatotal arthritis A/E affects more females/ Panciarticlar / RA factor +ve hence last last option is ANS- JRA MC in girls exceprt type – 2 pauciarticular and system's onses JRA which in more common in boys.



Psychiatry
1. Commonest psychiatric diagnosis depression.
2. Phychosis is associated with Deusion.
3. In a potient with mania drugs to be used is mood stabilizer.
4. Excessive buyinh is called oniomania.